EIAgen Toxoplasma IgG Avidity

brief description

Toxoplasma gondii is a ubiquitous protozoa which causes infection in all species of mammals. In man, serological studies have shown that a high percentage of the adult population becomes infected by this parasite. The disease is particularly dangerous during pregnancy, being transmitted from mother to fetus and causing serious malformations.

For this reason it is important to determine the antibody titer before the beginning of pregnancy if possible.

Sometimes it is not sufficient to test for IgM antibodies, as the presence of this class may be due to the persistence of IgM or asymtomatic reinfection by Toxoplasma, without risk for the fetus.

For this reason it is useful to assay the avidity of the IgG antibodies, in as far as it has been demonstrated that avidity is low in the acute phase of infection and increases over a period of time. The presence of low avidity antibodies is therefore an indication of a recent or current infection. The avidity of IgG antibodies in the serum can be assayed with this ELISA kit.

intended use

IMMUNOENZYMATIC METHOD FOR THE DETERMINATION OF THE AVIDITY OF ANTI TOXOPLASMA GONDII IgG ANTIBODIES IN HUMAN SERUM