EIAgen Cortisol

analyte

Steroids and Fertility

brief description

Cortisol is the principal glucocorticoid in the human: its systematic name is 11ß, 17 a, 21-trihydroxypregnene-3,20-dione and it is also known as 17-hydroxycorticosterone or hydrocortisone. Cortisol is released into the circulation from the cortex of the adrenal gland (the zonae fasciculata and reticularis) where it is synthesised from cholesterol. The synthesis and secretion of cortisol is closely controlled by the pituitary adrenocorticotropic hormone (ACTH); increased ACTH causes blood cortisol levels to rise, decreased ACTH causes blood levels to fall. ACTH is also the tropic hormone for the zonae fasciculata and reticularis.

intended use

EIAgen Cortisol a direct solid phase enzyme immunoassay for the quantitative measurement of Cortisol in human serum or plasma.