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EIAgen anti-Core 2 steps

analyte

HBcAb

brief description

The determination of Anti-HBc levels can be used to examine the progress of Hepatitis B virus (HBV) infection. In acute HBV infections, anti-HBc is detectable in the blood shortly after the appearance of HBsAg. Anti-HBc levels persist after HBsAg declines and are present before development of anti-HBs. During the interval between the disappearance of HBsAg and the development of anti-HBs, anti-HBc may be the only readily detectable serological marker of HBV infection. In chronic HBV infections, HBsAg rises during the incubation phase and may persist for years. Anti-HBc also appears during this early phase and reaches high titres which may persist for years. In asymptomatic HBV infections, HBsAg and HBeAg are present only briefly and are quickly followed by the appearance of anti-HBs and anti-HBc. Therefore, in such patients, sometimes the only evidence of an infection may be the detection of Anti-HBs and Anti-HBc.

intended use

EIAgen Anti-CORE 2 Steps kit is a solid phase enzyme immunoassay kit for the qualitative determination of total antibodies to Hepatitis B core antigen (Anti-HBc) in human serum or plasma.

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