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brief description

Carcinoembryonic Antigen (CEA) is a glycoprotein with a molecular weight of approximately 180,000 daltons which is produced by fetal entodermal epitelium. CEA was first isolated by Gold and Freedman in the mid 1960s from extracts of colorectal malignant tissues. In the adult CEA can be present at high level in patients with tumors of gastrointestinal tract and at other sites such as pancreas, ovary, breast, lung, prostate and uterus. Very high levels of CEA in serum can often be found in patients with a spread of the tumor to the liver. CEA is present in normal subjects at low levels and may be elevated in serum of about 14% of tobacco smokers. Elevated CEA levels in serum can also be found in subjects with inflammation such as ulcerative colitis, Crohn's disease, pancreatitis, liver disease, lung infection and in subjects with benign tumors.

intended use

EIAgen CEA is a direct solid phase enzyme immunoassay kit for quantitative determination of CEA in human serum.

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