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brief description

Human chorionic gonadotropin (hCG) is a sialoglycoprotein of molecular weight about 40,000. It is composed of two subunits of unequal size, a and ß. The a-subunit is virtually identical to that of the pituitary hormones hLH, hFSH, and hTSH. Biological specificity is conferred on these hormones by the differences in their ß-subunits, which also allows them to be distinguished immunologically. The hCG ß-subunit is similar to that of hLH, differing mainly in having extra C-terminal amino acids, and in being more heavily glycosylated. While the glycosylation has no effect on the action or immunological properties of hCG, it does affect its metabolism.

intended use

The Total hCG EIAgen kit has been designed for the quantitative determination of human chorionic gonadotropin (hCG) in human serum or plasma. The method can be used over range 1-500 mIU/ml (1st IRP 75/537) without dilution of the sample.

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