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brief description

Luteinizing Hormone (LH, lutropin) is a 29.4 kDa glycoprotein secreted by the anterior pituitary gland. The intact LH molecule is noncovalently-linked dimer containing alpha and beta subunits. The LH alpha subunit is homologous to the alpha subunits of several other glycoprotein hormones, including follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH),and human chorionic gonadotropin (hCG). However, each hormone has a unique beta subunit. Both LH and FSH production and secretion are stimulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. GnRH release is normally pulsatile, resulting in episodic release of both LH and FSH. LH production and secretion are regulated by a complex balance of endocrine feedback systems involving a number of hormones, including estrogen and progesterone.

intended use

EIAgen LH is a direct solid phase enzyme immunoassay for the quantitative determination of Luteinizing Hormone (LH) in human serum.

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