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brief description

Alpha-fetoprotein (AFP) is a fetal serum protein which circulates in trace amounts in healthy adults. AFP is produced mainly by the fetal yolk sac and fetal liver and to a lesser extent by the fetal gastrointestinal tract and kidneys. It is a single chain glycoprotein with a molecular weight of approximately 65-70 kilodaltons. Clinical interest in AFP is in oncology where serum AFP is used for the diagnosis and monitoring of tumours and in prenatal screening where amniotic fluid AFP is used to screen for foetal abnormalities such as spina bifida and Down's Syndrome.

intended use

The AFP EIAgen kit has been designed for the quantitative determination of Alphafetoprotein in human serum, plasma or amniotic fluid.

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