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brief description

Thyroid-stimulating hormone (TSH), or thyrotrophin, is a glycoprotein with a molecular weight of about 28,000 secreted by the pituitary gland. TSH is composed of two subunits of approximately equal size, called a and b. Other hormones such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH), both secreted by the pituitary, and chorionic gonadotrophin (hCG), produced by the placenta, have a subunits virtually identical to that of TSH, but there are important differences in their b subunits. These differences confer biological specificity on the complete molecules and allow them to be distinguished in immunoassays. Like the other glycoprotein hormones, TSH has a specific site of action which is the thyroid gland. Its main function is to regulate the release of thyroxine (T4) and the more biologically active triiodothyronine (T3), and to control different stages of their synthesis.

intended use

The U-TSH EIAgen kit has been designed for the quantitative determination of human Thyroid Stimulating Hormone (TSH) in human serum or plasma.

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