EIAgen ENA screen

brief description

The detection of Anti-Nuclear Antibodies (ANA) has long been an important tool in the diagnosis of systemic rheumatic diseases. The antigens used in their detection are purified by the saline extraction of human or animal nuclei, this has led to them being termed Extractable Nuclear Antigens (ENA). The most commonly measured ENA specifications are anti-SS-A/Ro, anti-SS-B/La, anti-Sm, anti-Sm/RNP, anti-Jo-1 and anti-Scl-70. The intracellular antigens SS-A/Ro, SS-B/La, Sm, Sm/RNP, Jo-1 and Scl-70 are targets for autoimmune responses in many patients with rheumatic diseases.

intended use

The EIAgen ENA Screen is an enzyme-linked immunosorbent assay method for the semi-quantitative determination of specific IgG autoantibodies to SSA/Ro, SS-B/La, Sm, Sm/RNP, Jo-1 and Scl-70 in human serum.