EIAgen Helicobacter pylori IgG

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Helicobacter pylori

brief description

In 1983, Warren and Marshall (1) identified Helicobacter pylori, a new gram-negative bacterial pathogen, in patients suffering from gastritis, and this finding led to studies on the relationship between bacterial infection and chronic gastric disease (2). It has been demonstrated that in patients with gastritis, eradication of the bacteria led to healing of the anatomical lesion (4). Diagnostic procedures for the detection of the organism generally involve invasive (gastroscopic) techniques for sample collection. However, a specific immune response is seen in infected patients. The serological test thus represents a useful alternative to the invasive bioptic technique. IgG levels rise with infection and remain constantly high until the infection is eliminated. The efficacy of antimicrobial therapy can therefore be monitored via changes in specific IgG antibody.

intended use

Immunoenzymatic kit for the determination of IgG-class antibodies to Helicobacter Pylori in human serum